SIPPAD · EXPERIMENTAL PROTEIN MAPPING

Protein Activity Mapper

Generate candidate peptides either by sliding-window length or by in-silico protease digestion, then interrogate the selected SAPIEN-Pep specialist engine and project activity back onto the parent protein.

Experimental research tool. Enzyme mode uses encoded cleavage rules to generate putative digestion products. It does not model digestion kinetics, enzyme concentration, accessibility, secondary structure or peptide abundance. SAPIEN-Pep prediction logic is unchanged.

Access key

Protein sequence / FASTA

Bioactivity to map

Fragment generation

Hotspot threshold

Minimum fragment length

Maximum fragment length

Minimum hotspot span

Activity map

Y-axis: fraction of resolved generated peptides covering each residue that were predicted positive. This is a computational activity landscape, not an experimentally measured residue-level activity.

Candidate hotspots

Start	End	Span	Protein segment	Mean positive fraction	Peak

Top positive peptides

Start	End	Length	Peptide	Generation	Source	Score