PepSilico
PRE-PUBLICATION ACCESS

SIPPAD

Sequence Intelligence Platform for Peptide Activity Discovery

Multi-activity peptide prediction, batch screening, multifunctional peptide selection, protein bioactivity mapping and interactive SAPIEN-Pep reasoning.

SAPIEN-Pep logo
SAPIEN-PepPrediction architecture
Symbolic AI for Peptide Intelligence Explainable Network
Restricted access. SIPPAD is deployed for private pre-publication testing. Predictions and reasoning traces are generated by the SAPIEN-Pep specialist engines. An access key is required.
Current mode

Peptide activity screening

Predict one or many peptides across ACE, DPP-IV and antimicrobial specialist engines, inspect reasoning, and select multifunctional candidates.

Experimental

Protein activity mapping

Scan a protein as overlapping fragments and project SAPIEN-Pep predictions back onto the parent sequence to identify bioactivity hotspots.

Open protein mapper →
Select activity or activities
Tick one activity or any combination. The same selections are applied to every peptide in a batch.
A single peptide opens the interactive reasoning network. Multiple peptides use the batch table. Maximum 500 peptides per batch.

Multifunctional peptide selection

Select at least two activities that must all be predicted positive. Peptides with a negative or unresolved prediction in any required activity are excluded.